Could mild herbal stimulants such as the coca leaf, khat, kratom or ephedra offer alternatives to the more concentrated substances that now dominate the market? Could the recreational stimulants market be steered towards a less harmful direction over time through differentiating the control mechanisms between plants and synthesized derivatives? Different legal regimes are currently implemented between countries and vary greatly for the different plants, some of which are erroneously classified as new psychoactive substances (NPS).

  • Submission to the House of Commons Select Committee on the cocaine trade

    Memorandum on the coca leaf
    Martin Jelsma
    Transnational Institute (TNI)
    June 12, 2009

    The attached summary report addresses the myths that surround the coca leaf and is presented to the Committee members in order to allow them to make an evidence-based judgement on its current legal status and on the potential usefulness of coca in its natural form, including in the UK context.

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  • Los mitos de la coca

    Anthony Henman Pien Metaal
    TNI Drogas y conflicto documentos de debate No. 17
    Junio de 2009

    La historia ha sido injusta con la hoja de coca, denegando su distribución a escala mundial a pesar de su demostrado valor como potenciador de energía, y limitando su posible uso como una alternativa sana a todo tipo de estimulantes químicos disponibles actualmente en el mercado internacional.

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  • Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence

    Marie Longo, Wendy Wickes, Matthew Smout, Sonia Harrison, Sharon Cahill & Jason M. White
    Addiction 105, pp. 146–154
    June 2009

    This study tested the impact of a long-acting form of amphetamine as medication to help control dependent use of the closely allied stimulant, methamphetamine. Prescribed usually for the treatment of pathological sleepiness or attention deficit/hyperactivity disorder, effects of the amphetamine tablets prescribed in the study take several hours longer to emerge than normal amphetamine and last three to six hours longer, giving it a 'smoothing' profile similar to methadone for heroin users; non-rapid onset make it less intensely pleasurable, and longer duration suits it to once-daily administration.

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  • Substitution therapy for amphetamine users

    James Shearer, John Sherman, Alex Wodak and Ingrid van Beek
    Drug and Alcohol Review (2002) 21, pp. 179•-185
    June 2002

    The illicit use of amphetamines continues to be a growing problem in many countries around the world, yet treatment responses remain in need of further development. This is particularly true with regards to pharmacotherapy for amphetamine dependence. In this Harm Reduction Digest four authors who bring together considerable research and clinical experience in this area describe the nature of amphetamine-related problems and consider the role of amphetamine agonists in substitution therapy for amphetamine dependence.

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