Some of the parts: Is marijuana’s “entourage effect” scientifically valid?
Industry players swear pot’s many chemicals work in concert, but most scientists hear a THC solo
Thursday, April 20, 2017
If you believe budtender wisdom, consuming a strain called Bubba Kush should leave you ravenous and relaxed whereas dank Hippie Chicken should uplift you like a dreamy cup of coffee. But if you take pure, isolated delta-9-tetrahydrocannabinol, or THC—the main psychoactive ingredient in marijuana—you’ll experience “a high that has no specific character, so that seems boring,” says Mowgli Holmes, a geneticist and founder of a cannabis genetics company Phylos Bioscience. What gives cannabis “character,” in Holmes’s view, are the hundreds of other chemicals it contains. These include THC’s cousin cannabinoids such as cannabidiol, along with other compounds called terpenes and flavonoids.