Serotonin helps curb cocaine addiction
Only one in five consumers get addicted to cocaine, thanks to the protective role played by serotonin, scientists at the University of Geneva (UNIGE) have foundOnly one in five consumers get addicted to cocaine, thanks to the protective role played by serotonin, scientists at the University of Geneva (UNIGE) have found
Friday, September 10, 2021
The team has revealed a brain mechanism specific to cocaine which triggers a massive increase in serotonin (the ‘happy’ hormone) in addition to the increase in dopamine (the neurotransmitter that causes addiction) common to all drugs. Serotonin acts as an intrinsic brake on the overexcitement of the reward system prompted by dopamine. The results are published in the latest edition of the prestigious journal Science. Contrary to popular thinking, cocaine only triggers an addiction in 20% of consumers, a statement issued by the university said. “The same principle applies to all potentially addictive products,” said Christian Lüscher, a professor in the Department of Basic Neurosciences at the UNIGE Faculty of Medicine, who led the research.
